Mean concentration-time profiles (means ± SDs, ng/ml) in plasma following oral administration of AFX or IVM in scabies-infested pigs. Concentrations measured at hour 2, 4, 6, and 24 of D0 for AFX and IVM and on D2, 4, 5, 8 (4 h after the second IVM dose), 10, 14, 21, 28, 35, 45, and 50 posttreatment are depicted. D, day; AFX, afoxolaner; IVM, ivermectin.