Mean concentration-time profiles (means ± SDs, ng/g) in skin following oral administration of AFX or IVM in scabies-infested pigs. Concentrations measured on D1, 2, 4, 5, 8 (4 h after the second IVM dose), 10, 14, 21, 28, 35, 45, and 50 posttreatment are depicted. *, outlier measured concentrations. D, day; AFX, afoxolaner; IVM, ivermectin.