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. 2018 Aug 27;62(9):e00851-18. doi: 10.1128/AAC.00851-18

TABLE 1.

Classification of BLNAS, low-BLNAR, and high-BLNAR isolates and their susceptibilities to β-lactamsa

Genotype Group No. of strains MIC (mg/liter)
Ampicillin
Ceftriaxone
Cefotaxime
Geometric mean MIC50 MIC90 Range Geometric mean MIC50 MIC90 Range Geometric mean MIC50 MIC90 Range
BLNAS 35 0.4 0.5 0.5 0.35–0.5 ≤0.06 ≤0.06 ≤0.06 ≤0.06–0.25 ≤0.06 ≤0.06 ≤0.06 ≤0.06–2
Low-BLNAR II 5 1.15 1 2 0.5–2 ≤0.06 ≤0.06 ≤0.06 ≤0.06 ≤0.06 ≤0.06 ≤0.06 ≤0.06–0.25
High-BLNAR III 47 3.77 4 8 2–16 0.28 0.25 1 ≤0.06–1 1.34 2 4 ≤0.06–8
High-BLNAR III-like 9 5.44 8 16 2–16 0.16 0.25 0.25 ≤0.06–0.5 2.59 4 8 0.25–8
a

Five BLPAR isolates and 2 BLPACR isolates possessed blaTEM-1 and were excluded from this table. The PBP3 type of the BLPACR isolates was group III. The high-BLNAR isolate SMHi90 was excluded because of its unique ftsI sequence (see Fig. S1 and S2 in the supplemental material).