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Arithmetic mean (SD) plasma concentration-time profiles of murepavadin in healthy subjects (n = 8) and subjects with mild (n = 8), moderate (n = 8), or severe (n = 8) renal function impairment after administration of a single dose of 2.2 mg infused over 3 h on a semilogarithmic scale. Mild RI, mild renal function impairment; moderate RI, moderate renal function impairment; severe RI, severe renal function impairment; healthy, normal renal function.
