. 2018 Aug 27;62(9):e00490-18. doi: 10.1128/AAC.00490-18

TABLE 3.

Group comparisons of renal function groups, characterized by CL_Cr

Parameter	Intrasubject CV (%)^a	Group ratio^b	LSmean^c		Point estimate	90% confidence interval (%)
Parameter	Intrasubject CV (%)^a	Group ratio^b	Test	Reference	Point estimate	90% confidence interval (%)
AUC_0–∞ (h · mg/liter)	22.78	1/4	49.66	27.24	1.82	1.51–2.20
		2/4	60.53	27.24	2.22	1.84–2.69
		3/4	69.99	27.24	2.57	2.12–3.11
C_max (mg/liter)	18.61	1/4	6.33	4.52	1.40	1.20–1.64
		2/4	6.79	4.52	1.50	1.28–1.75
		3/4	5.92	4.52	1.31	1.12–1.53

CV, coefficient of variation.

Group 1, mild renal function impairment; group 2, moderate renal function impairment; group 3, severe renal function impairment; group 4, normal renal function.

LSmean, least square mean.