TABLE 2.

MICs, resistance genes, and plasmid profiles of mcr-1-positive E. coli isolates

Isolate	MIC (μg/ml)a												mcr-1 plasmid (size in kb)	Other resistance genesb
	CAZ	CTX	MEM	IPM	ETP	AMP	GEN	AMK	CIP	LVX	NIT	CST
DC2562	≥64	≥32	1	2	4	≥32	4	2	>16	16	32	8	IncI1 (62)	blaCTX-M-1, blaOXA-48,* aac(6')-Ib-cr, qnrA, gyrA(S83L), parC(S80I)
DC90	≥64	≥32	1	2	2	≥32	2	2	>16	>16	64	8	IncP (33)	blaCTX-M-9,* blaOXA-48, aac(6')-Ib-cr, qnrA, parC(S80I G144V), gyrA(S83L)
DC3411	16	≥32	0.015	0.125	0.5	≥32	2	2	>16	16	16	4	NDc	blaCTX-M-9, blaTEM, aac(6')-Ib-cr, qnrA
DC3539	32	≥32	0.015	0.125	0.5	≥32	>64	16	>16	16	64	16	IncI1 (62)	blaCTX-M-1,* blaCTX-M-9, aac(6')-Ib-cr, qnrA
DC3599	32	≥32	0.03	0.06	0.5	≥32	64	16	>16	16	64	8	IncI1 (62)	blaCTX-M-1, blaCTX-M-9,* aac(6')-Ib-cr, qnrA
DC3658	32	≥32	0.015	0.125	0.5	≥32	2	4	16	4	64	8	IncW (62)	blaCTX-M-1, blaCTX-M-9,* aac(6')-Ib-cr, qnrA, qnrD
DC3802	≥64	≥32	0.03	0.125	0.5	≥32	>64	2	>16	16	8	4	IncFIB (62)	blaCTX-M-1, blaCTX-M-9,* aac(6')-Ib-cr, gyrA(S83L)
DC3806	≥64	≥32	0.03	0.125	0.5	≥32	>64	2	>16	>16	32	8	ND	blaCTX-M-1, blaCTX-M-9, aac(6')-Ib-cr, qnrA
DC3846	≥64	≥32	0.03	0.5	0.5	≥32	>64	4	>16	>16	64	16	IncFIB (62)	blaCTX-M-1, blaCTX-M-9,* aac(6')-Ib-cr, qnrA, qnrD
DC4887	16	≥32	0.015	0.125	0.5	4	>64	2	>16	8	16	8	IncFIB (62)	blaCTX-M-1,* aac(6')-Ib-cr, gyrA(S83L)
DC5262	≥64	≥32	1	1	0.5	4	16	8	0.5	1	16	8	IncFIB (62)	blaTEM-1,* aac(6')-Ib-cr, parC(S80I)
DC5286	≥64	≥32	0.03	0.125	0.5	2	2	4	>16	16	16	8	IncFIB (62)	blaCTX-M-1,* aac(6')-Ib-cr, gyrA(S83L)
EC600	0.5	2	0.03	0.125	0.06	4	2	2	0.25	0.5	8	0.5	ND	ND

^aCAZ, ceftazidime; CTX, cefotaxime; MEM, meropenem; IPM, imipenem; ETP, ertapenem; AMP, ampicillin; GEN, gentamicin; AMK, amikacin; CIP, ciprofloxacin; LVX, levofloxacin; NIT, nitrofurantoin; CST, colistin.

^bAsterisks represent the genes that were coidentified in the transconjugants.

^cND, not detected.