FIG 4.
Replication capacities of the INSTI-resistant mutants, using a single-round infection assay. The replication capacities of the INSTI-resistant mutants used in this study were measured using INSTI-resistant mutant vectors in a single-round infection assay. The luciferase activity of the WT virions was set to 100, and the infectivities of the mutant vectors (adjusted for the amount of p24/Gag used in the assay) were measured relative to WT infectivity. The error bars represent the standard deviations of independent experiments; n = 4.