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Probabilities of achieving each Cmax (A) and AUCτ (B) in simulated subjects treated with pyrazinamide. Each target value has been reported previously, as indicated in Materials and Methods. The target attainment was performed based on the following weight bands: 5 to 7 kg (circles), 8 to 14 kg (triangles), 15 to 20 kg (squares), and 21 to 30 kg (asterisks). The dashed lines represent 90% of target attainment. The target AUCτ is 363 μg · h/ml.
