Total no. of patients |
113 |
Age (yr) |
5.00 (2.17–8.25) |
Wt (kg) |
14.3 (9.70–20.1) |
Serum creatinine (μmol/liter) |
36.0 (27.3–47.8) |
Sex |
|
Male |
63 |
Female |
50 |
HIV infection |
|
Positive |
59 |
Negative |
54 |
NAT2 genotype |
|
Slow |
51 |
Intermediate |
50 |
Fast |
12 |
Dose (mg/kg) |
|
Rifampin |
15.8 (13.6–18.8) |
Isoniazid |
11.0 (9.06–12.8) |
Pyrazinamide |
24.7 (22.6–29.7) |
Ethambutol |
16.8 (15.0–20.3) |
Wt band (kg) in simulation (n) |
|
5–7 (16,000) |
Wt (kg): 6.45 (6.17–7.25) |
|
Age (yr): 0.960 (0.650–1.42) |
8–14 (41,000) |
Wt (kg): 12.5 (10.1–13.4) |
|
Age (yr): 4.00 (2.17–5.00) |
15–20 (27,000) |
Wt (kg): 17.7 (16.0–19.5) |
|
Age (yr): 6.50 (5.25–8.92) |
21–30 (21,000) |
Wt (kg): 22.4 (21.9–24.2) |
|
Age (yr): 9.83 (8.25–11.92) |