FIG 1.

(A) Induction of autophagy in BMMs by ambroxol as determined by LC3B puncta. (B) Induction of autophagy in BMMs by ambroxol as determined by TFEB nuclear translocation. (C) Effects of ambroxol on M. tuberculosis Erdman survival in free culture and when infected into BMMs. Data are means ± SEM of 3 or 4 independent replicates. Tukey's multiple comparison: *, P < 0.05; **, P < 0.01; †, not significant. (D) Effect of ambroxol on autophagy in lung tissue. n = 2 mice/group. Data are means ± SEM.