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Logarithmic correlations between mCLCR and different parameters. (A) Serum concentrations of PIP at 50% of the dosage interval and mCLCR. (B) Serum trough concentrations of PIP at T0 and mCLCR (ml/min). (C) Total body clearance (CL) of PIP and mCLCR. (D) Serum trough concentrations of MEM at T0 and mCLCR. PIP, piperacillin; mCLCR, measured creatinine clearance; MEM, meropenem.
