TABLE 4.

Polymorphisms of Pfmdr1 and K13-propeller in Plasmodium falciparum isolates

Gene (ID)	Referencea			Mutationb			No. of isolates			Prevalence (% [95% CI])d
	Codon position	AAc	Codon	AA	Codon	Base position	PCR positive	Sequenced	With mutation
pfmdr1 (PF3D7_0523000)	102	G	ggt	G	ggC	306			4	2.07 (0.06–4.08)
	102	G	ggt	G	ggC/T	306			4	2.07 (0.06–4.08)
	130	E	gaa	K/E	A/Gaa	388	211	193	1	0.52 (−0.49–1.53)
	156	D	gat	N	Aat	466			1	0.52 (−0.49–1.53)
	182	G	ggt	G	ggG	546			1	0.52 (−0.49–1.53)
	182	G	ggt	G	ggG/T	546			1	0.52 (−0.49–1.53)
	1069	T	act	T	acG	3207			11	5.29 (2.25–8.33)
	1069	T	act	T	acG/T	3207			2	0.96 (−0.37–2.29)
	1113	G	ggt	A	gCt	3338	211	208	1	0.48 (−0.46–1.42)
	1142	P	cct	P	ccA	3426			1	0.48 (−0.46–1.42)
	1157	T	aca	T	acG	3471			1	0.48 (−0.46–1.42)
	1196	D	gat	N	Aat	3586			2	0.96 (−0.37–2.29)
	1226	F	ttt	Y	tAt	3677			1	0.48 (−0.46–1.42)
	1230	G	gga	G	ggC	3690			1	0.48 (−0.46–1.42)
k13-propeller (PF3D7_1343700)	550	S	tct	S	tcC	1650	199	184	2	1.09 (−0.41–2.59)
	561	R	cgt	H	cAt	1682			1	0.54 (−0.52–1.6)
	575	R	aga	R/K	aA/Ga	1724			1	0.54 (−0.52–1.6)
	589	V	gtc	I	Atc	1765			1	0.54 (−0.52–1.6)

^aReference sites are underlined.

^bMutation sites are underlined.

^cAA, amino acid residue.

^dCI, confidence interval.