. 2018 Sep 5;8:13276. doi: 10.1038/s41598-018-31517-z

Table 1.

Demographics.

	Control (n = 50)	PD (n = 131)	PDD (n = 27)	MSA (n = 24)	PSP (n = 14)
Age	65.3 (8.6)	64.9 (10.6)	72.3 (5.9)^a,d	63.8 (8.0)^g	71.5 (6.2)^c,f,j
Number (female %)	50 (56%)	131 (39%)^c	27 (26%)^c	24 (50%)	14 (64%)ⁱ
TD/PIGD dominant	NA	60/60, 1 UD	5/20^f, 2 UD	NA	NA
LEDD	NA	520.1 (422.2)	892.3 (563.6)^d	633.8 (567.2)	523.4 (297.9)ⁱ
Disease duration (years)	NA	5.5 (4.8)	14.2 (6.6)^d	7.2 (4.5)^f,g	5.7 (2.3)^g
Hoehn & Yahr score	NA	2.0 (0.8)	3.0 (0.8)^d	4.1 (0.9)^d,g	4.1 (0.6)^d,g
UPDRS-3 score	1.5 (2.5)	17.1 (10.5)^a	35.4 (14.4)^a,d	45.1 (19.2)^a,d,i	45.4 (14.2)^a,d,i
MMSE	27.8 (4.3)	28.4 (1.6)	22.1 (6.0)^a,d	27.7 (2.4)^g	23.7 (7.9)^b,d,k
Letter S Fluency	17.4 (6.0)	14.5 (5.8)^b	7.7 (4.1)^a,d	12.9 (6.1)^b,h	8.5 (5.4)^a,e
ADAS Delayed Recall	2.3 (1.8)	3.2 (2.3)^c	6.1 (2.8)^a,d	3.2 (2.3)^g	4.6 (2.6)^b,f
AQT*	62.5 (14.1)	73.8 (28.8)^b	173.9 (98.0)^a,d	93.2 (63.0)^b,g	188.0 (118.4)^a,d,j
FACIT-f	10.1 (6.2)	14.9 (8.2)^a	24.1 (11.9)^a,d	23.9 (8.8)^a,s	24.4 (11.9)^a,f
HADS Depression	1.7 (2.6)	3.9 (3.5)^a	7.7 (4.1)^a,d	7.2 (4.2)^a,d	6.3 (3.9)^a,f
HADS Anxiety	2.7 (4.0)	5.0 (4.2)^a	6.6 (4.5)^a	7.4 (4.6)^a,f	6.9 (4.6)^b
Total somatic illness	0.52 (0.68)	0.47 (0.68)	0.44 (0.64)	0.58 (0.72)	0.57 (0.65)

Total somatic illness is a composite score of the presence of the four most common comorbidities (cardiovascular disease, asthma/allergies, osteoarthritis and diabetes mellitus). The data are presented as the mean and SD. Significance levels were analyzed using Mann-Whitney except for gender differences where the chi-square test was used.

NA = not applicable.

UD = undetermined.

*Patients who could not perform AQT were assigned a result of 360 sec.

^ap < 0.001 vs. controls; ^bp < 0.01 vs. controls; ^cp < 0.05 vs. controls.

^dp < 0.001 vs. PD; ^ep < 0.01 vs. PD; ^fp < 0.05 vs. PD.

^gp < 0.001 vs. PDD; ^hp < 0.01 vs. PDD; ⁱp < 0.05 vs. PDD.

^jp < 0.01 vs. MSA; ^kp < 0.05 vs. MSA.