Table 3.
YKL-40 | MCP-1 | CRP | SAA | IL-6 | IL-8 | α-syn | Tau | P-tau | Aβ42 | |
---|---|---|---|---|---|---|---|---|---|---|
MCP-1 | NS | |||||||||
CRP | 0.143* | NS | ||||||||
SAA | 0.153* | NS | 0.669*** | |||||||
IL-6 | NS | NS | NS | 0.139* | ||||||
IL-8 | 0.253*** | 0.158* | 0.182** | 0.218*** | 0.285*** | |||||
α-syn | 0.363*** | NS | NS | 0.160* | NS | 0.209** | ||||
Tau | 0.4135*** | NS | NS | 0.161* | − 0.188** | NS | 0.736*** | |||
P-tau | 0.359*** | NS | NS | NS | NS | 0.160 * | 0.789*** | 0.731*** | ||
Aβ42 | NS | NS | NS | NS | NS | NS | 0.406*** | NS | 0.213*** | |
NfL | 0.376*** | 0.218*** | 0.149* | 0.196** | NS | 0.243*** | 0.137* | 0.367*** | NS | −0.157* |
Correlations between different CSF biomarkers in the cohort as a whole, corrected for age, gender, disease duration, total somatic illness and inflammatory conditions, given as β-values.
For α-syn only samples with Hb <200 ng/L was included.
*significant for <0.05. **Significant for <0.01. ***Significant for <0.001.
NS = Not Significant.