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. 2018 Sep 5;8:13301. doi: 10.1038/s41598-018-31489-0

Table 4.

Cox Proportional Hazards modeling for overall survival in patients with mutations in the mtDNA ETC genes (n = 194).

Variables Hazard Ratio 95% CI p-value
Age 1.02 1.00 1.03 0.037
Cytogenetic Risk
  Intermediate 3.22 1.65 6.28 0.001
  Poor 5.35 2.42 11.8 <0.001
Transplant Status 0.44 0.29 0.68 <0.001
DNMT3A 1.47 0.96 2.25 0.080
RUNX1 1.82 0.96 3.44 0.066
TP53 2.00 1.02 3.94 0.044
mtDNA ETC 1.44 0.79 2.62 0.229