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. 2018 Sep 5;8:13239. doi: 10.1038/s41598-018-31427-0

Table 4.

Significantly enriched transcription factors for positional candidate genes for CHL_fat and CHL_milk.

Traita Transcription factor Overlap p-value
CHL_fat CREB1 40/3057 0.002
CHL_fat PPARD 11/516 0.004
CHL_fat CEBPB 9/382 0.005
CHL_fat MYC 14/797 0.006
CHL_fat GRHL2 16/1000 0.009
CHL_fat CIITA 9/459 0.014
CHL_fat CLOCK 8/407 0.020
CHL_fat NANOG 13/840 0.022
CHL_fat FOXP3 19/1404 0.023
CHL_fat E2A 25/2000 0.023
CHL_fat SMAD4 25/2000 0.023
CHL_fat FOXA1 25/2000 0.023
CHL_fat TFAP2A 24/1904 0.024
CHL_fat TAL1 23/1875 0.035
CHL_fat MITF 57/5578 0.036
CHL_fat ATF3 26/2189 0.036
CHL_fat EST1 14/1001 0.038
CHL_fat CTCF 24/2000 0.039
CHL_fat EOMES 13/932 0.045
CHL_fat NFIB 9/573 0.048
CHL_milk LXR 60/2000 1.00E-11
CHL_milk DACH1 46/1698 1.00E-07
CHL_milk SMC4 51/2000 1.19E-07
CHL_milk BCL6 39/2000 0.001
CHL_milk P68 39/2000 0.001
CHL_milk ZNF274 11/327 0.002
CHL_milk P300 38/2000 0.003
CHL_milk EZH2 20/935 0.008
CHL_milk EGR1 91/6207 0.010
CHL_milk KDM2B 35/2000 0.013
CHL_milk MYCN 7/234 0.022
CHL_milk NOTCH1 7/245 0.028
CHL_milk ERG 8/321 0.039
CHL_milk PRDM5 19/1029 0.039
CHL_milk FOXO3 14/695 0.039
CHL_milk EWS-FLI1 12/574 0.043

aCHL_fat: mg of cholesterol in 100 g of fat, CHL_milk: mg of cholesterol in 100 g of milk.