. 2018 Sep 5;6(17):e13821. doi: 10.14814/phy2.13821

Table 1.

Cohort characteristics

Variable	Infant 1		Infant 2		Infant 3		Infant 4		Infant 5		Infant 6
Variable	Time 1	Time 2	Time 1	Time 2	Time 1	Time 2	Time 1	Time 2	Time 1	Time 2	Time 1	Time 2
GA at birth (weeks)	23		29		27		23		27		24
Birthweight (g)	505		592		814		513		730		710
Apgar score at 5 min	6		9		9		6		8		6
Gender	Female		Female		Male		Female		Male		Male
GA at start of sildenafil and maximum daily dose	44 weeks 8 mg/kg		43 weeks 6 mg/kg		36 weeks 6 mg/kg		26 weeks 6 mg/kg		–		–
GA at postnatal steroids	27		–		34		32		31		30
Duration between 1st postnatal steroid dose & captopril (completed weeks)	27		–		7		15		14		9
Corrected GA at start of captopril and reassessment (completed weeks)	54	59	53	58	41	44	47	51	45	50	39	44
Ventilation mode	NIMV	HF	CPAP	HF	NIMV	NIMV	NIMV	CPAP	CPAP	LF	CPAP	HF
MAP (cm)/L of water	13	9	8	8	14	14	14	10	8	300 mL/min	9	7
Oxygen requirement (%)	40	28	45	30	60	34	100	27	28	25	55	30
pCO2	68	56	70	55	79	77	91	67	67	58	65	53
Discharge ventilation	HF 14, FiO₂ 0.26 × 18 h & LF 0.25 L/min × 6 h		HF 14, FiO₂ 0.4 × 18 h & LF 0.25 L/min × 6 h		HF 15, FiO₂ 0.25 × 18 h & LF 0.25 L/min × 6 h		HF 10, FiO₂ 0.21 × 18 h & LF 0.2 L/min × 6 h		LF 0.1L/min FiO₂ 0.25		LF 0.15 L/min FiO₂ 0.25

GA – gestational age, MAP – mean airway pressure, L – liters, pCO₂ – partial pressure of carbon dioxide, HF – high flow, CPAP – continuous positive airway pressure, NIMV – noninvasive mandatory ventilation, FiO₂ – fractional inspired oxygen, LF – low flow.