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IKBKAP SSO treatment increases IKAP protein expression. Transfections of IKBKAP SSO (12 nM) into control (GMO2912) or FD fibroblasts (GMO4589, GMO4663) restore splicing of IKBKAP exon 20 (top). Western blotting shows an increase in IKAP protein expression after transfection with IKBKAP SSO into FD fibroblasts but not control fibroblasts. hnRNP H was used as a loading control. Transfections were performed in triplicates.
