Table 1. General characteristics of the patients according to the location of the OLP lesion.
| Characteristics | OLP lesion | Total (n=113) | P value | |||
|---|---|---|---|---|---|---|
| Mucosal lesion (n=78) | Gingival lesion (n=10) | Mixed lesion (n=25) | ||||
| Age (yr) | 58.8±13.4 | 60.1±10.2 | 53±8.8 | 57.6±12.4 | 0.157 | |
| Female | 56 (71.8) | 6 (60) | 17 (68) | 79 (69.9) | 0.725 | |
| Medical history | ||||||
| Circulatory problems | 23 (29.5) | 4 (40) | 7 (28) | 34 (30.1) | 0.766 | |
| Endocrine problems | 5 (6.4) | 1 (10) | 3 (12) | 9 (8.0) | 0.648 | |
| Digestive problems | 0 (0) | 2 (20) | 0 (0) | 2 (1.8) | <0.001a) | |
| Rheumatic problems | 3 (3.9) | 0 (0) | 0 (0) | 3 (2.7) | 0.501 | |
| Menopause | 28 (35.9) | 0 (0) | 4 (16) | 32 (28.3) | 0.018a) | |
| Malignancy | 5 (6.4) | 0 (0) | 4 (16) | 9 (8) | 0.190 | |
| Symptoms of OLP | ||||||
| Pain | 11 (14.1) | 4 (40) | 1 (4) | 16 (14.2) | 0.022a) | |
| Hypersensitivity | 47 (60.3) | 5 (50) | 13 (52) | 65 (57.5) | 0.676 | |
| Subtype of OLP | 0.007a) | |||||
| White or red lesion | 71 (91) | 6 (60) | 23 (92) | 92 (87.6) | ||
| Erosive lesion | 3 (3.8) | 3 (30) | 2 (8) | 8 (7.6) | ||
| Mixed | 4 (5.1) | 1 (10) | 0 (0) | 5 (4.8) | ||
| Mode of dexamethasone treatment | 0.840 | |||||
| Ointment alone | 2 (2.8) | 0 (0) | 1 (4.2) | 3 (2.8) | ||
| Gargle alone | 52 (72.2) | 6 (60) | 16 (66.7) | 74 (69.8) | ||
| Gargle + ointment | 18 (25) | 4 (40) | 7 (29.2) | 29 (27.4) | ||
| Pattern of dexamethasone use | 0.166 | |||||
| Continuous | 72 (92.3) | 8 (80) | 20 (80) | 100 (88.5) | ||
| Intermittent | 6 (7.7) | 2 (20) | 5 (20) | 13 (11.5) | ||
| Duration of dexamethasone use (day) | 131.1±190.1 | 204.4±331.3 | 186.5±189.1 | 149.8±205.3 | 0.344 | |
| Adverse effects | 3 (3.9) | 0 (0) | 2 (8) | 5 (4.4) | 0.527 | |
| Response | 0.078 | |||||
| No change | 11 (14.1) | 2 (20) | 1 (4) | 14 (12.4) | ||
| Improved | 58 (74.4) | 5 (50) | 16 (64) | 79 (69.9) | ||
| New lesion | 9 (11.5) | 3 (30) | 8 (32) | 20 (17.7) | ||
| Follow-up (day) | 702.2±1,021 | 710.6±1,073.6 | 1,229.1±1,297.9 | 819.5±1,103.8 | 0.109 | |
Values are presented as mean ± standard deviation or number (%). Circulatory problems included hypertension, cardiovascular disease, and dyslipidemia. Endocrine problems included hypothyroidism and diabetic mellitus. Rheumatic problems included asthma, Sjögren syndrome, and Behçet disease. Digestive problems included gastrointestinal trouble and hepatitis C. Adverse effects included dry mouth, facial swelling, nausea, and weight gain.
OLP: oral lichen planus.
a)Statistically significant difference compared to the baseline.