Table I.
Preoperative characteristics of locally advanced unresectable pancreatic ductal adenocarcinoma patients preparing for conversion surgery with GnP therapy.
| No. | Age/gender | Location | Factors determining unresectability | Period of Tx (months) | CA19-9 (before Tx) (U/ml) | CA19-9 (after Tx) (U/ml) | Reduction rate of CA19-9 (%) | RECIST |
|---|---|---|---|---|---|---|---|---|
| 1 | 61/M | Head | Contact with SMA 360° | 5 | 0.8 | 0.1 | 87.5 | PR |
| 2 | 56/F | Head | Contact with CHA with extension to hepatic artery bifurcation | 3.9 | 150.4 | 35.2 | 76.6 | PR |
| 3 | 45/M | Body | Contact with CEA | 2.4 | 2909 | 884 | 69.6 | SD |
| 4 | 71/M | Body | Contact with SMA and CEA | 1.4 | 165.7 | 35.4 | 78.0 | SD |
| 5 | 77/M | Head | Contact with SMA >270° | 3.8 | 726.0 | 51.3 | 92.8 | PR |
| Present case | 43/M | Head | Contact with SMA >270° | 9 | 205.7 | 67.5 | 67.1 | SD |
CEA, celiac artery; CHA, common hepatic artery; F, female; M, male; PR, partial response; RECIST, Response Evaluation Criteria in Solid Tumor; SD, stable disease; Tx, chemotherapy.