Table 10.
Summary of Recommendations
| Recommendations | Evidence (According to GRADE [21, 22]) |
|---|---|
| The annual use of CgA, PP, and glucagon as a tumor marker for the diagnosis of NF-pNETs is not recommended. | (1|⊕⊕⊕○) |
| Radiological screening for NF-pNET should include MRI or endoscopic ultrasonography. | (2|⊕⊕○○) |
| 68Ga-DOTA PET/CT should be preferred over 111In single photon emission CT/CT for the diagnosis of NF-pNETs. | (1|⊕⊕○○) |
| 68Ga-DOTA PET/CT should not be routinely used for the diagnosis of NF-pNETs. | (2|⊕○○○) |
| Based on the growth rate and NF-pNET size, pancreatic visualization can be extended to once per 1 to 2 y. | (2|⊕⊕○○) |
| Screening for NF-pNETs in asymptomatic MEN1 patients should not be extended until the age of 16. | (2|⊕○○○) |
Abbreviation: GRADE, Grading of Recommendations, Assessment, Development, and Evaluation.