Table 2.
Baseline Characteristics of Community-Dwelling Older Adults with Atrial Fibrillation According to Warfarin Treatment
| Characteristic | Not Treated, n = 1,029, 56.3% |
Treated, n = 798, 43.7% |
P-Value | Standardized Mean Difference |
|---|---|---|---|---|
| Age, mean ± SD | 85.4 ± 7.5 | 83.1 ± 6.3 | <.001 | −33.6 |
| Male, n (%) | 356 (34.6) | 297 (37.2) | .25 | 5.5 |
| Activities of daily living, mean ± SD | 46.4 ± 17.3 | 39.9 ± 19.1 | <.001 | −35.5 |
| Cognitive status, mean ± SD | 6.1 ± 3.6 | 4.7 ± 3.5 | <.001 | −37.8 |
| Nursing care needs, mean ± SD | 7.9 ± 8.6 | 7.3 ± 7.8 | .34 | −7.5 |
| Mobility, mean ± SD | 31.9 ± 11.4 | 29.7 ± 11.9 | <.001 | −18.6 |
| Pressure sore risk, mean ± SD | 5.9 ± 6.1 | 4.3 ± 5.9 | <.001 | −26.9 |
| Social support, mean ± SD | 160.6 ± 70.4 | 151.1 ± 69.3 | .01 | −13.6 |
| Multidimensional Prognostic Index based on the Standardized Multidimensional Assessment Schedule for Adults and Aged Persons | ||||
| Continuous, mean ± SD | 0.4 ± 0.2 | 0.4 ± 0.2 | <.001 | −24.9 |
| 1 (mild risk), n (%) | 325 (31.6) | 380 (47.6) | <.001 | 33.2 |
| 2 (moderate risk), n (%) | 389 (37.8) | 245 (30.7) | .06 | −15.0 |
| 3 (severe risk), n (%) | 315 (30.6) | 173 (21.7) | <.001 | −20.4 |
| Congestive Heart Failure, Hypertension, Age, Diabetes, Stroke, Vascular disease, Age, Sex score, mean ± SD |
3.8 ± 1.0 | 3.8 ± 0.9 | .09 | 1.4 |
| Past treatment rate tertile, n (%)a | ||||
| First (low) | 410 (39.8) | 272 (34.1) | .01 | −12.0 |
| Second (medium) | 313 (30.4) | 211 (26.4) | .06 | −8.8 |
| Third (high) | 306 (29.7) | 315 (39.5) | <.001 | 20.6 |
| Fractures, n (%) | 13 (1.3) | 19 (2.4) | .07 | 8.4 |
| Cancer, n (%) | 175 (17.0) | 103 (12.9) | .02 | −11.5 |
| Dementia, n (%) | 286 (27.8) | 169 (21.2) | .00 | −15.4 |
| Stroke, n (%) | 105 (10.2) | 69 (8.7) | .26 | −5.3 |
| Cardiovascular disease, n (%) | 109 (10.6) | 173 (21.7) | <.001 | 30.5 |
| Respiratory disease, n (%) | 33 (3.2) | 30 (3.8) | .52 | 3.0 |
| Neurologic disease, n (%) | 47 (4.6) | 39 (4.9) | .75 | 1.5 |
| Hypokinetic syndrome, n (%) | 161 (15.7) | 98 (12.3) | .04 | −9.7 |
| Other diseases, n (%) | 100 (9.7) | 98 (12.3) | .08 | 8.2 |
a
Number of all medications per month taken before enrollment.
SD = standard deviation.