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. 2018 Sep 4;10:327–340. doi: 10.1016/j.omtm.2018.07.005

Figure 4.

Figure 4

AAV-Mediated Correction of Lysosomal Storage in Non-neuronal Tissues in Eyes and Peripheral Tissues

(A and B) MPS II mice were injected i.v. with 5 × 1012 vg/kg scAAV9-mCMV-hIDS at age 1 month. Eye (A) and peripheral tissues (B) were assayed at 7 months pi (age 8 months) by immunofluorescence for LAMP 1 (red fluorescence). Blue fluorescence indicates DAPI-stained nuclei. Con, cornea; Cil, ciliary process; Irs, iris; LIV, liver; BC, bronchiole; HRT, heart; KID, kidney. G, glomerulus.