Table I.
Effects of Rb1 on neurological deficit scores in rats 24 h after reperfusion.
Groups | Rat no. (n) | Neurological scores |
---|---|---|
Sham | 8 | 0.00±0.00b |
MCAO | 8 | 2.07±0.24 |
Rb1 50 mg/kg | 8 | 1.71±0.43 |
Rb1 100 mg/kg | 8 | 1.25±0.72a |
Rb1 200 mg/kg | 8 | 1.05±0.36b |
Data are presented as the mean ± standard deviation. Animals received different doses of Rb1 or saline vehicle following the onset of ischemia. Neurological deficit scores were evaluated after 24 h of reperfusion according to the Longa's method.
P<0.05
P<0.01 vs. MCAO. RB1, Ginsenoside Rb1; MCAO, middle cerebral artery occlusion.