Table 3.
Comparison of cytokine concentration of study subjects classified by positive or negative rhinovirus infection versus control.
| Cytokines (pg/mL) | Control (N=30) | Asthma with RV− (N=52) | Asthma with RV+ (N=63) | P ∗∗ |
|---|---|---|---|---|
| Non-Th2-related cytokines | ||||
| IL-2 | 4.21 ± 2.88 | 1.27 ± 2.43 | 1.86 ± 3.17 | <0.05∗,∗∗, NS∗∗∗ |
| IL-8 | 7.58 ± 7.40 | 6.02 ± 5.65 | 10.37 ± 15.42 | NS∗,∗∗,∗∗∗ |
| IL-10 | 5.28 ± 9.78 | 13.44 ± 16.52 | 4.57 ± 6.87 | <0.05∗,∗∗∗; NS∗∗ |
| TNF-α | 3.61 ± 8.46 | 7.94 ± 37.02 | 7.65 ± 32.13 | <0.05∗,∗∗, NS∗∗∗ |
| IFN-γ | 77.56 ± 66.43 | 46.47 ± 68.13 | 63.50 ± 53.94 | NS∗,∗∗,∗∗∗ |
|
| ||||
| Th2-related cytokines | ||||
| GM-CSF | 18.93 ± 48.54 | 14.70 ± 29.46 | 38.04 ± 44.79 | NS∗,∗∗,∗∗∗ |
| IL-4 | 0.86 ± 0.32 | 3.91 ± 1.30 | 4.32 ± 2.56 | <0.05∗,∗∗; NS∗∗∗ |
| IL-5 | 0.89 ± 0.78 | 1.85 ± 2.16 | 2.79 ± 2.73 | <0.05∗,∗∗,∗∗∗ |
| IL-13 | 2.02 ± 1.92 | 2.05 ± 1.51 | 3.99 ± 6.46 | NS∗; <0.05∗∗,∗∗∗ |
RV: rhinovirus; RV+: positive RV infection; RV−: negative RV infection. ∗Asthma with RV− versus control; ∗∗asthma with RV+ versus control; ∗∗∗asthma with RV+ versus asthma with RV−.