Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 17;16(4):4391–4399. doi: 10.3892/ol.2018.9153

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Bai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 2. — Immunohistochemical analysis of MIB2 expression in normal brain tissues and primary glioma tumors. (A) Representative images from IHC assays of normal brain tissues and specimens of 69 archived glioma cases. (a,b) Normal brain tissue; (c,d) WHO grade 1 pilocytic astrocytoma; (e,f) WHO grade 2 diffuse astrocytoma; (g,h) WHO grade 3 anaplastic astrocytoma; (i,j) WHO grade 4 glioblastoma multiforme. (a,c,e,g,i) Magnification, ×200. (b,d,f,h and j) Magnification, ×400. (B) Comparative statistical quantification of the mean values of MIB2 staining between normal brain tissues (n=3) and glioma specimens of different WHO grades. Student's t-test was used for statistical analysis. **P<0.01. IHC, immunohistochemistry; MIB2, E3 ubiquitin-protein ligase; WHO, World Health Organization.