Table IV.
Comparison of patient habits and relative mRNA expression levels of ITGA3, ITGA5, ITGB1 and ITGB6 genes in oral squamous cell carcinoma samples with control samples (oral tissue from the tumor-free margin).
| ITGA3 | ITGA5 | ITGB1 | ITGB6 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Habits | n (total=55) | Mean ± SD | P-valuea | Mean ± SD | P-valuea | Mean ± SD | P-valuea | Mean ± SD | P-valuea |
| Alcohol | 0.83 | 0.11 | 0.68 | 0.18 | |||||
| No | 9 | 3.02±3.60 | 4.66±3.38 | 1.91±2.26 | 4.53±5.73 | ||||
| Yes | 46 | 2.02±8.42 | 1.27±7.18 | 2.65±8.27 | 0.39±8.22 | ||||
| Betel quid chewing | 0.65 | 0.33 | 0.81 | 0.75 | |||||
| No | 5 | 3.59±5.84 | 4.25±5.21 | 0.73±3.33 | 3.74±7.03 | ||||
| Yes | 50 | 2.05±8.02 | 1.59±6.93 | 2.70±7.90 | 0.80±8.08 | ||||
| Cigarette smoking | 0.84 | 0.45 | 0.86 | 0.40 | |||||
| No | 5 | 3.51±4.90 | 3.53±6.61 | 1.13±2.31 | 4.56±6.98 | ||||
| Yes | 50 | 2.05±8.07 | 1.66±6.86 | 2.66±7.94 | 0.71±8.05 | ||||
Data are presented as mean ΔΔCq values (ΔCq of OSCC-ΔCq of its matched oral tissue from the tumor-free margin).
a
Mann-Whitney U test. SD, standard deviation; ITGA3, integrin subunit α3; ITGA5, integrin subunit α5; ITGB1, integrin subunit β1; ITGB6, integrin subunit β6.