Table V.
Different cut-offs and their relative sensitivity and specificity for ITGA3, ITGA5, ITGB1 and ITGB6 genes in patients with oral squamous cell carcinoma.
| A, All locations | ||||||||
| ITGA3 | ITGA5 | ITGB1 | ITGB6 | |||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity, % | Specificity, % | Cut-off | Specificity, % | Cut-off | Specificity, % | Cut-off | Specificity, % | Cut-off |
| 50.91 | 90.91 | 63.20 | 83.64 | 56.26 | 70.91 | 61.93 | 74.55 | 57.90 |
| 61.82 | 85.45 | 62.87 | 78.18 | 55.00 | 50.91 | 61.17 | 61.82 | 57.21 |
| 67.27 | 67.27 | 61.94 | 63.64 | 54.35 | 45.45 | 60.96 | 58.18 | 57.06 |
| B, Locations 2/3 | ||||||||
| ITGA3 | ITGA5 | ITGB1 | ITGB6 | |||||
| Sensitivity, % | Specificity, % | Cut-off | Specificity, % | Cut-off | Specificity, % | Cut-off | Specificity, % | Cut-off |
| 64.00 | 92.00 | 62.97 | 84.00 | 55.00 | 64.00 | 61.07 | 84.00 | 57.90 |
| 68.00 | 88.00 | 62.67 | 84.00 | 55.00 | 64.00 | 60.99 | 80.00 | 57.65 |
| 76.00 | 76.00 | 61.73 | 76.00 | 53.94 | 60.00 | 60.78 | 60.00 | 56.61 |
All locations including the locations 1, 2, 3 and 4. Location 1, buccal mucosa/retromolar area; location 2, tongue/mouth floor; location 3, edentulous ridge; location 4, others (lower lip/vestibule/soft palate); ITGA3, integrin subunit α3; ITGA5, integrin subunit α5; ITGB1, integrin subunit β1; ITGB6, integrin subunit β6.