Table III.
Multivariate analysis of potential prognostic factors for GBC.
| Variables | Hazards ratio | 95% CI | P-valuea |
|---|---|---|---|
| Stage by UICC 8th (19) | 6.25 | 3.81–10.26 | <0.001 |
| Stage III and IV vs. Stage I and II | |||
| Age, years | |||
| ≥60 vs. <60 | 1.09 | 0.92–1.29 | 0.316 |
| Sex | |||
| Male vs. female | 0.077 | 0.57–1.02 | 0.072 |
| Surgical procedure | |||
| Curative vs. palliative | 0.11 | 0.07–0.17 | <0.001 |
| Lymph nodes involvement | |||
| N1 and N2 vs. N0 | 1.56 | 1.14–2.14 | 0.003 |
| Distant metastasis | |||
| M1 vs. M0 | 2.37 | 1.64–3.43 | <0.001 |
a
Multivariate analyses were applied to assess the prognostic value of UICC 8th edition staging for GBC and other potential predictors using Cox regression proportional hazards model.