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. 2018 Jul 26;16(4):4201–4210. doi: 10.3892/ol.2018.9221

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — RFC5 enriched cell cycle and DNA damage process in lung cancer. Gene set enrichment analysis was performed by GSEA using the GSE3141 dataset. The gene profile of high RFC5 expression groups (top 50%) and low RFC5 expression groups (bottom 50%) were loaded to the GSEA software, and the ‘c5.all.v5.1’ gene set was selected to process the analysis. (A) RFC5 high expression enriched DNA replication, (B) replication fork, (C) mitotic cell cycle, (D) cell cycle process, (E) DNA repair, (F) response to DNA damage stimulus signature genes. GSEA, gene set enrichment analysis; NES, normal enrichment score; NOM P-value, normal P-value; FDR q-value, false discovery rate q-value.