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. 2018 Jul 26;16(4):4201–4210. doi: 10.3892/ol.2018.9221

Table V.

Enrichment of biological processes in the RFC5 high expression group.

No. GS details Size ES NES NOM P-value FDR q-value
  1 DNA replication 88 0.607 2.085 0.002 0.037
  2 Chromosomal part 88 0.667 2.083 <0.001 0.020
  3 DNA-dependent DNA replication 47 0.672 2.072 0.002 0.015
  4 Chromosome 114 0.632 2.071 <0.001 0.012
  5 DNA metabolic process 232 0.518 2.026 <0.001 0.018
  6 Double-strand break repair 22 0.739 2.013 0.002 0.019
  7 Nuclear part 487 0.527 1.988 <0.001 0.024
  8 Nuclear membrane 47 0.651 1.985 <0.001 0.022
  9 Nuclear pore 28 0.761 1.982 <0.001 0.020
10 Nuclear membrane part 39 0.688 1.958 <0.001 0.026
11 Nuclear envelope 67 0.607 1.951 <0.001 0.026
12 Organelle lumen 391 0.512 1.940 <0.001 0.027
13 Membrane-enclosed lumen 391 0.512 1.940 <0.001 0.025
14 Mitotic cell cycle 136 0.571 1.922 0.006 0.029
15 DNA repair 117 0.533 1.918 <0.001 0.029
16 Envelope 158 0.587 1.912 <0.001 0.030
17 Organelle envelope 158 0.587 1.912 <0.001 0.028
18 Translation factor activity nucleic acid binding 29 0.696 1.908 <0.001 0.029
19 RNA splicing 66 0.651 1.907 <0.001 0.027
20 Cell cycle process 172 0.539 1.905 0.006 0.027

Statistical analyses were performed using the gene set enrichment analysis software. GS, gene sets; ES, enrichment score; NES, normal enrichment score; NOM, normal; FDR, false discovery rate; RFC5, replication factor C 5.