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. 2018 Sep 3;20(10):1008–1022. doi: 10.1016/j.neo.2018.08.005

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Supplementary Figure S7 — Pharmacological inhibition of MCT-1 activity impairs AXL-dependent cell invasion in EAC cells. (A) Lactate assay measuring lactate secretion in the CM of vehicle-treated versus SR13800-treated SK-GT-4 cells or vehicle-treated versus SR13800-treated FLO-1 cells. (B-E) Transwell invasion assay. (B) Transwell invasion assay representative images (20×) of vehicle- versus SR13800-treated SK-GT-4 cells or (D) vehicle- versus SR13800-treated FLO-1 cells. (C) Transwell invasion assay quantification as the number of invading vehicle- versus SR13800-treated SK-GT-4 cells or (E) vehicle- versus SR13800-treated FLO-1 cells. Data are presented as median ± SD. (F) Trypan blue viability assay of SK-GT-4 or FLO-1 cells following treatment with vehicle or SR13800.