Table 1.
Characteristics of the Study Participants
| No. (%) |
||||
|---|---|---|---|---|
| Characteristic | Overall | No OAG | OAG | P Value |
| Total | 25420 (100) | 24202 (95.2) | 1218 (4.8) | |
| Age, mean (SD), y | 66.1 (5.8) | 66.1 (5.8) | 66.6 (5.9) | .003 |
| Race/ethnicitya | ||||
| White | 19 232 (84.1) | 18 398 (84.6) | 834 (75.5) | |
| Black | 1252 (5.5) | 1127 (5.2) | 125(11.3) | <.001 |
| Latino | 1558 (6.8) | 1458 (6.7) | 100 (9.1) | |
| Asian | 600 (2.6) | 565 (2.6) | 35 (3.2) | |
| Other | 218 (1.0) | 208 (1.0) | 10 (0.9) | |
| Sex | ||||
| Male | 11308 (44.5) | 10767 (44.5) | 541 (44.4) | .96 |
| Female | 14112 (55.5) | 13435 (55.5) | 677 (55.6) | |
| Any statin usedb | 15 898 (62.5) | 15152 (62.6) | 746 (61.3) | .34 |
| Type of statin used exclusivelyb | ||||
| Lovastatin | 616 (3.9) | 586 (3.9) | 30 (4.0) | |
| Cerivastatin | 31 (0.2) | 29 (0.2) | 2 (0.3) | |
| Atorvastatin | 5492 (34.6) | 5253 (34.7) | 239 (32.0) | |
| Rosuvastatin | 387 (2.4) | 371 (2.5) | 16(2.1) | .59 |
| Fluvastatin | 191 (1.2) | 182 (1.2) | 9(1.2) | |
| Pravastatin | 968 (6.1) | 921 (6.1) | 47 (6.3) | |
| Simvastatin | 3271 (20.6) | 3126 (20.6) | 145 (19.4) | |
| Using multiple statin types | 4942 (31.1) | 4684 (30.9) | 258 (34.6) | |
| Other cholesterol-lowering medication use | 6356 (25.0) | 6062 (25.1) | 294 (24.1) | .47 |
| Statin strength used exclusively, mgb | ||||
| 10 | 3099 (19.5) | 2972 (19.6) | 127 (17.0) | |
| 20 | 2882 (18.1) | 2751 (18.2) | 131 (17.6) | .38 |
| 40 | 1857 (11.7) | 1768 (11.7) | 89(11.9) | |
| 80 | 356 (2.2) | 336 (2.2) | 20 (2.7) | |
| Using multiple statin strengths | 7704 (48.5) | 7325 (48.3) | 379 (50.8) | |
| Baseline LDL cholesterol level, mg/dL | ||||
| <82 | 4541 (17.9) | 4326 (17.9) | 215(17.7) | |
| 82–130 | 13 623 (53.6) | 12 988 (53.7) | 635 (52.1) | .62 |
| 130–177 | 6339 (24.9) | 6017 (24.9) | 322 (26.4) | |
| 177–225 | 917 (3.6) | 871 (3.6) | 46 (3.8) | |
Abbreviations: LDL, low-density lipoprotein; OAG, open-angle glaucoma.
a
Excluding 2560 with missing data on race/ethnicity.
b
Excluding 9522 who were not taking statins.