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. 2018 Jun 18;17(9):1750–1765. doi: 10.1074/mcp.RA118.000824

Fig. 3.

Fig. 3.

Mycolactone-mediated Sec61 blockade prevents the production of viral Type I/II but not Type III TMPs. Surface expression of viral envelope proteins HA (A), NA (B) and M2 (C) as well as HLA components B2M (D) and HLA-A2b (E), in HEK293 cells infected with IAV for 1h prior to incubation with Mycolactone, or vehicle as control. MFI: mean fluorescence intensity; hpi: hours post infection. Data shown are MFI ± S.E. (n = 3) from one of two independent experiments, which gave similar results. MFIs of mycolactone-treated cells were compared with vehicle controls using a t test with Holm-Sidak correction for multiple testing. *p < 0.05; **p < 0.01; ***p < 0.001; ***p < 0.001; ns: no significant difference.