TABLE 2.
Percentage Increases in SUVmean, SUVmax, and SUR
| SUVmean |
SUVmax |
SUR |
||||||||||
| Tracer | Study | ROIs | Motion (mm)* | CTAC | NAC | AIM | CTAC | NAC | AIM | CTAC | NAC | AIM |
| 18F-FDG | 1 | 17 | 5.3 (2.0–8.3) | 16.7 ± 19.5 | 18.2 ± 19.2 | 21.1 ± 18.4 | 13.9 ± 14.4 | 15.6 ± 16.0 | 15.6 ± 10.0 | 33.2 ± 22.3 | 35.0 ± 21.9 | 40.5 ± 21.3 |
| 2 | 106 | 5.4 (1.7–9.4) | 24.6 ± 26.6 | 22.4 ± 23.5 | 28.0 ± 28.7 | 19.7 ± 22.5 | 21.2 ± 26.1 | 22.6 ± 24.2 | 26.5 ± 27.0 | 21.1 ± 23.3 | 27.9 ± 26.8 | |
| 3 | 1 | 6.9 | 6.9 | 4.9 | 20.2 | −0.4 | 0.1 | 20.5 | 13.2 | 7.8 | 26.9 | |
| 4 | 25 | 8.4 (2.5–16.2) | 38.5 ± 48.8 | 30.8 ± 48.8 | 42.2 ± 50.3 | 26.6 ± 50.0 | 20.9 ± 50.6 | 29.2 ± 57.0 | 37.3 ± 48.4 | 29.5 ± 48.3 | 43.1 ± 50.6 | |
| 5 | 28 | 8.3 (3.8–25.2) | 13 ± 19.4 | 16.3 ± 21.2 | 19.3 ± 20.6 | 10.6 ± 23.8 | 14.5 ± 28.9 | 11.2 ± 21.1 | 12.0 ± 19.2 | 15.2 ± 21.0 | 19.3 ± 20.6 | |
| 6 | 3 | 3.0 (1.6–4.2) | 7.0 ± 3.8 | 2.8 ± 6.8 | 10.2 ± 2.0 | 6.4 ± 5.7 | 2.0 ± 5.9 | 6.6 ± 4.5 | 6.7 ± 3.8 | 0.4 ± 6.6 | 9.8 ± 2.0 | |
| 7 | 3 | 3.6 (1.3–5.8) | 2.6 ± 2.7 | 3.5 ± 3.3 | 5.6 ± 3.5 | 5.2 ± 6.1 | 2.6 ± 6.2 | 5.9 ± 5.6 | 9.6 ± 2.9 | 11.7 ± 3.6 | 11.9 ± 3.8 | |
| 8 | 88 | 8.7 (1.8–14.0) | 24.9 ± 20.1 | 25.3 ± 19.9 | 31.3 ± 23.2 | 23.1 ± 19.5 | 23.8 ± 19.3 | 27.7 ± 20.6 | 19.6 ± 19.3 | 21.3 ± 19.3 | 28.0 ± 22.7 | |
| 9 | 36 | 7.0 (1.8–14.7) | 2.9 ± 7.5 | 5.7 ± 6.5 | 15.1 ± 12.7 | −0.1 ± 13.6 | 2.8 ± 12.3 | 9.3 ± 14.5 | −1.5 ± 7.2 | 2.4 ± 6.3 | 12.2 ± 12.4 | |
| 10 | 16 | 4.6 (2.6–7.3) | 3.4 ± 7.1 | 2.0 ± 10.0 | 5.7 ± 7.9 | 3.2 ± 6.1 | 2.4 ± 12.6 | 5.9 ± 11.0 | 19.9 ± 8.3 | 17.4 ± 11.5 | 21.7 ± 9.1 | |
| Mean† | 6.1 | 14.0 | 13.2 | 19.9 | 10.8 | 10.6 | 15.5 | 17.6 | 16.2 | 24.1 | ||
| 18F-FPDTBZ | 1 | Kidney | 11.7 | 24.3 | 28.8 | 28.5 | 6.9 | 8.3 | 9.9 | 26.6 | 28.6 | 32.0 |
| Pancreas | 9.2 | 23.1 | 28.3 | 27.9 | 5.8 | 8.6 | 8.2 | 25.4 | 28.0 | 31.4 | ||
| Spine | 1.4 | −3.1 | −19.7 | −2.9 | −2.0 | −21.6 | −1.9 | −1.3 | −19.9 | −0.3 | ||
| 2‡ | Kidney | 14.7 | 31.2 | 25.7 | 34.4 | 20.3 | 23.0 | 21.9 | — | — | — | |
| Pancreas | 14.2 | 17.5 | 17.7 | 17.9 | 5.4 | 5.0 | 5.3 | — | — | — | ||
| Spine | 2.8 | −0.7 | −35.6 | −1.6 | −3.8 | −24.0 | −5.5 | — | — | — | ||
| 18F-FMISO | 1 | Large tumor (avid area) | 11.8 | 9.6 | 10.9 | 11.1 | 1.6 | 1.9 | 2.1 | 12.9 | 14.9 | 14.9 |
| Small tumor | 5.3 | 15.0 | 21.1 | 21.6 | 8.6 | 17.1 | 17.3 | 18.4 | 25.5 | 25.8 | ||
*
Mean and range of motion amplitudes estimated between end-inspiration and end-expiration gates across all lesions for each subject.
†
10 studies (323 ROIs).
‡
No SUR result is reported for study 2 since heart was out of field of view.