Table 2.
Comparison of patient characteristics across different dementia subtypes
| Characteristics | Vascular dementia (n=3,908)
|
Alzheimer’s disease (n=1,525)
|
Other dementia subtypes (n=23,017)
|
P-value | |||
|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | ||
| Mean age, in years (mean ± SD) | 74.20±9.96 | 77.28±7.08 | 77.15±9.07 | <0.0001 | |||
| Age group (years) | <0.0001 | ||||||
| ≤64 | 692 | 17.71 | 39 | 2.56 | 1,309 | 5.69 | |
| 65–74 | 1,104 | 28.25 | 506 | 33.18 | 6,761 | 29.37 | |
| 75–84 | 1,558 | 39.87 | 745 | 48.85 | 10,505 | 45.64 | |
| ≥85 | 554 | 14.18 | 235 | 15.41 | 4,442 | 19.30 | |
| Sex | <0.0001 | ||||||
| Female | 1,848 | 47.29 | 900 | 59.02 | 12,803 | 55.62 | |
| Male | 2,060 | 52.71 | 625 | 40.98 | 10,214 | 44.38 | |
| Level of education | 0.0008 | ||||||
| Primary school (≤6 years) | 2,646 | 67.71 | 1,032 | 67.67 | 16,093 | 69.92 | |
| Secondary school (7–9 years) | 460 | 11.77 | 147 | 9.64 | 2,380 | 10.34 | |
| High school (10–12 years) | 477 | 12.21 | 186 | 12.20 | 2,517 | 10.94 | |
| Bachelor or above (≥13 years) | 325 | 8.32 | 160 | 10.49 | 2,027 | 8.81 | |
| Marital status | <0.0001 | ||||||
| Married | 2,413 | 61.75 | 923 | 60.52 | 13,037 | 56.64 | |
| Divorced/spouse deceased | 1,333 | 34.11 | 569 | 37.31 | 8,874 | 38.55 | |
| Unmarried | 162 | 4.15 | 33 | 2.16 | 1,106 | 4.81 | |
| Comorbidities | |||||||
| Hypertension | 3,087 | 78.99 | 974 | 63.87 | 15,597 | 67.76 | <0.0001 |
| Cerebrovascular disease | 2,916 | 74.62 | 503 | 32.98 | 9,300 | 40.40 | <0.0001 |
| Diabetes | 1,488 | 38.08 | 426 | 27.93 | 7,009 | 30.45 | <0.0001 |
| COPD | 994 | 25.44 | 318 | 20.85 | 6,480 | 28.15 | <0.0001 |
| Hyperlipidemia | 1,135 | 29.04 | 339 | 22.23 | 5,084 | 22.09 | <0.0001 |
| Depression | 595 | 15.23 | 197 | 12.92 | 3,965 | 17.23 | <0.0001 |
| Kidney disease | 528 | 13.51 | 164 | 10.75 | 2,948 | 12.81 | 0.0236 |
| Congestive heart failure | 431 | 11.03 | 129 | 8.46 | 2,574 | 11.18 | 0.0045 |
| Head injury | 315 | 8.06 | 86 | 5.64 | 1,726 | 7.50 | 0.0092 |
| Schizophrenia | 46 | 1.18 | 12 | 0.79 | 372 | 1.62 | 0.0067 |
| Acute myocardial infarction | 77 | 1.97 | 21 | 1.38 | 304 | 1.32 | 0.0063 |
| Charlson comorbidity score (mean ± SD) | 3.67±2.00 | 2.25±1.89 | 2.97±2.01 | <0.0001 | |||
| Pain-related diagnoses | |||||||
| At least one pain-related diagnosis | 1,612 | 41.25 | 747 | 48.98 | 11,601 | 50.40 | <0.0001 |
| Osteoarthritis | 924 | 23.64 | 430 | 28.20 | 6,972 | 30.29 | <0.0001 |
| Headache | 376 | 9.62 | 199 | 13.05 | 2,991 | 12.99 | <0.0001 |
| Osteoporosis | 337 | 8.62 | 173 | 11.34 | 2,741 | 11.91 | <0.0001 |
| Cancer | 278 | 7.11 | 126 | 8.26 | 1,882 | 8.18 | 0.0735 |
| Vertebral fracture | 178 | 4.55 | 80 | 5.25 | 1,378 | 5.99 | 0.0012 |
| Hip fracture | 146 | 3.74 | 55 | 3.61 | 1,126 | 4.89 | 0.0009 |
| Rheumatoid arthritis | 43 | 1.10 | 20 | 1.31 | 340 | 1.48 | 0.1716 |
| Migraine | 52 | 1.33 | 13 | 0.85 | 301 | 1.31 | 0.3006 |
| Wrist fracture | 33 | 0.84 | 12 | 0.79 | 286 | 1.24 | 0.0370 |