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. 2018 Aug 31;11:5371–5381. doi: 10.2147/OTT.S170775

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© 2018 Gao et al. This work is published and licensed by Dove Medical Press Limited

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STARD13 overexpression attenuates HCC cell stemness.

Notes: (A and B) STARD13 mRNA and protein expressions were examined in adherent HCC cells and nonadherent spheres. (C and D) The expression of stemness markers (ALDH1 and Nanog) was detected in HCC cells with STARD13 overexpression or not. (E and F) Cell spheroid potential (sphere’s size and number) was measured in cells depicted in (C). (G) ALDH1 activity was evaluated in cells depicted in (C). Data were presented as mean ± SD; ^*P<0.05; ^**P<0.01 vs adherent cells, HepG2, or Huh7.

Abbreviations: HCC, hepatocellular carcinoma; STARD13, StAR-related lipid transfer domain 13.