Table 3.
Characteristics of Study Participants by Tertiles of HOMA-IR in the BLSA
| Characteristic |
HOMA-IR
|
P Value a | ||
|---|---|---|---|---|
| <1.23 (n = 155) | 1.23–2.18 (n = 155) | >2.18 (n = 155) | ||
| Age, y | 70 (11) | 71 (10) | 70 (9) | 0.57 |
| Male sex, % | 45.16 | 54.84 | 53.55 | 0.18 |
| BMI (kg/m2) | 24.5 (3.3) | 26.6 (3.4) | 29.0 (4.2) | <0.0001 |
| Current smoking, % | 1.3 | 3.2 | 1.3 | 0.36 |
| Systolic blood pressure, mm Hg | 116 (15) | 119 (16) | 121(12) | 0.005 |
| Diastolic blood pressure, mm Hg | 66 (8) | 65 (9) | 66 (8) | 0.23 |
| Triglycerides, mg/dL | 81 (31) | 95 (41) | 122 (56) | <0.0001 |
| Total cholesterol, mg/dL | 196 (35) | 186 (34) | 192 (42) | 0.04 |
| LDL cholesterol, mg/dL | 114 (32) | 106 (30) | 114 (38) | 0.08 |
| HDL cholesterol, mg/dL | 65 (17) | 60 (15) | 54 (15) | <0.0001 |
| Hypertension, % | 27.7 | 49.7 | 56.1 | <0.0001 |
| Diabetes, % | 4.5 | 7.1 | 18.7 | <0.0001 |
| Coronary artery disease, % | 3.9 | 5.2 | 9.7 | 0.08 |
| Stroke, % | 6.4 | 7.7 | 3.9 | 0.34 |
| Heart failure, % | 3.9 | 7.1 | 5.2 | 0.45 |
| Cancer, % | 5.8 | 10.3 | 7.1 | 0.31 |
| Chronic kidney disease, % | 25.2 | 24.5 | 27.1 | 0.86 |
Values are presented as mean (SD) or percentages.
a
χ 2 tests for categorical variables, Kruskal-Wallis tests for continuous variables.