Table 4.
Partial correlation coefficients among control subjects between concentrations of selected serum hormones, sex hormone–binding globulin, insulin-like growth factor I, and prostate-specific antigen*
| Compound | Testosterone (n = 7143) | Free testosterone (n = 6479) | DHT (n = 1715) | Androstanediol glucuronide (n = 3377) | DHEA-S (n = 2147) | Androstenedione (n = 2525) | Estradiol (n = 3399) | Free estradiol (n = 3062) | SHBG (n = 6626) | PSA (n = 3937) |
|---|---|---|---|---|---|---|---|---|---|---|
| Testosterone | 1 | |||||||||
| Free testosterone | 0.76 | 1 | ||||||||
| DHT | 0.60 | 0.29 | 1 | |||||||
| Androstanediol glucuronide | 0.17 | 0.24 | 0.14 | 1 | ||||||
| DHEA-S | 0.04 | 0.12 | 0.01 | 0.15 | 1 | |||||
| Androstenedione | 0.24 | 0.25 | 0.26 | 0.19 | 0.47 | 1 | ||||
| Estradiol | 0.29 | 0.29 | 0.22 | 0.18 | 0.05 | 0.17 | 1 | |||
| Free estradiol | −0.02 | 0.31 | −0.07 | 0.18 | 0.09 | 0.11 | 0.87 | 1 | ||
| SHBG | 0.51 | −0.15 | 0.33 | −0.03 | −0.07 | 0.08 | 0.05 | −0.41 | 1 | |
| PSA | 0.08 | 0.11 | −0.01 | 0.02 | 0.05 | 0.05 | −0.04 | −0.01 | −0.03 | 1 |
| IGF-I | −0.02 | 0.07 | 0.01 | −0.04 | 0.05 | 0.02 | −0.03 | 0.02 | −0.12 | 0.07 |
*
Data are partial correlation coefficients of log-transformed hormone concentrations that were adjusted for age at blood collection (in four groups) and study. n = the number of control subjects with a measurement for that hormone; DHT = dihydrotestosterone; DHEA-S = dehydroepiandrosterone sulfate; SHBG = sex hormone–binding globulin; PSA = prostate-specific antigen; IGF-I = insulin-like growth factor I.