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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Pharmacol Biochem Behav. 2018 Jul 26;173:74–83. doi: 10.1016/j.pbb.2018.07.009

Table 2.

The effect of oxycodone as compared to saline on the median (25%:75%) latency in seconds for dams to retrieve the first and last pup back to the nest following a 1h separation.

PND3* PND6 PND9
First Pup Last Pup First Pup Last Pup First Pup Last Pup
Saline (n=12) 32 (11:52) 179 (116:300) 41 (8:80) 179 (69:441) 75 (26:250) 203 (76:447)

Oxycodone (n=9) 145 (84:480) 447 (245:480) 119 (79:480) 405 (244:480) 111 (14:454) 241 (77:480)

Mann-Whitney U 12 19 26.5 29 53 53
P value 0.005 0.02 0.05 0.08 1.0 0.97
*

significant difference in latency to retrieve pups