. Author manuscript; available in PMC: 2019 Sep 1.

Published in final edited form as: J Neurooncol. 2018 May 31;139(3):651–659. doi: 10.1007/s11060-018-2910-9

Table 1.

Quantitative measures of all diffusional metrics at pre- and post-chemoradiation.

	Overall Survival

Variables	Hazard ratio	95% CI		p-value
Age	0.303	0.057	0.86	0.007^*
CET Volume	0.703	0.415	1.059	0.1
MGMT status	0.02	0	1.658	0.093

ADC slope (μm²/s)	1.177	1.016	1.482	0.002^*

Age	0.922	0.766	1.111	0.354
CET Volume	0.963	0.752	1.287	0.751
MGMT status	0.814	0.427	1.123	0.813

Dapp slope (μm²/s)	0.991	0.925	1.033	0.706
Kapp slope (a.u)	0.952	0.744	1.109	0.563

Age	0.924	0.729	1.102	0.371
CET Volume	0.923	0.735	1.151	0.449
MGMT status	0.573	0.03	6.082	0.646

DDC slope (μm²/s)	1.006	0.986	1.029	0.519
α slope (a.u)	1.079	0.81	1.46	0.582

Mean, standard deviation (Std-Dev) and coefficient of variation (CV) were reported for each fit and ROI. The results of normality test (Shapiro-Wilk test) as well as corresponding Student’s or Wilcoxon-Mann-Whitney tests were reported for each fit and ROI