Fig. 1.
Analysis of peripheral adult haematopoiesis upon Yap/Taz loss. a–c Peripheral blood analysis of Yapflox/flox/Tazflox/flox (Y/T f/f) or YapΔ/Δ/TazΔ/Δ (Y/T Δ/Δ) mice. a WBCs, b RBCs, and c hemoglobin at 4, 6, and 10 months post recombination. d–f FACS analysis of BMCs: d Lineage-negative cells, e LSK progenitors, and f HSCs (Lin-, Kit+, Sca+, CD48−, CD150+, and CD34− cells). g Kaplan–Meier survival analysis (M: males, F: females). h, i Peripheral blood analysis: h RBCs and i WBCs. l, m coBMT experiments: l Chimerism assessed at different time points post-BMT. inj = donor cells mix. m Chimerism of the secondary coBMTs, as in l