Table 2.
Molecular alterations that suppress EMT
| Molecular alterations | Signalling pathways | References |
|---|---|---|
| ARID1A | – | [201] |
| CBL-B | AKT/ERK | [202] |
| CMTM3 | STAT3/Twist1/EMT | [203] |
| DDAH1 | WNT/β-Catenin | [204] |
| FBXL5 | – | [205] |
| FBXW7 | RhoA/p53 | [33, 34, 206–211] |
| HOXB9 | – | [30, 212, 213] |
| NMI | NFκB/p65 | [214] |
| PAQR3 | Raf/MAPK PI3K/AKT | [19, 215, 216] |
| PDK1 | – | [217] |
| PPARγ | – | [218] |
| Rap1GAP | – | [219] |
| RKIP | Notch1 | [220–222] |
| TOP1MT | – | [223] |
| miR-BART6-3p | – | [224] |
| miR-7 | IGF | [225] |
| miR-22 | – | [69] |
| miR-23b | Notch2 | [226] |
| miR-128 | PI3K/AKT | [227] |
| miR-143, miR-145 | – | [228] |
| miR-200b | – | [229] |
| miR-216a | JAK2/STAT3 | [230] |
| miR-338-3p | MET/AKT/PTEN | [25, 231–233] |
| miR-551b | – | [234] |
| miR-1271 | – | [21] |
| miR-2392 | – | [32] |