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. 2018 Sep 6;8:13328. doi: 10.1038/s41598-018-31806-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Increase in diagnostic accuracy to predict IDH genotype after combination of parameters (relative difference to accuracy of respective single parameter). GLCM: Grey-level co-occurrence matrix; GLNUr: Grey-level non-uniformity for run; HGRE: High grey-level run emphasis; LRE: Long-run emphasis; LRHGE: Long-run high grey-level emphasis; LRLGE: Long-run low grey-level emphasis; LZE: Long-zone emphasis; NGLDM: Neighborhood grey-level different matrix; RLNU: Run length non-uniformity; RP: Run percentage; SkewnessH: Skewness of histogram; SRE: Short-run emphasis; SRHGE: Short-run high grey-level emphasis; SZE: Short-zone emphasis; SZHGE: Short-zone high grey-level emphasis; TBR: tumor-to-brain ratio; TTP: time to peak; ZLNU: Zone length non-uniformity; ZP: Zone percentage.