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. 2018 Aug 29;15(145):20180272. doi: 10.1098/rsif.2018.0272

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© 2018 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 1. — Sketch of the basic model. (a) Three different modes of cell division in the focal progenitor compartment. Blue cells are cells within the compartment, red cells differentiate and leave the compartment. The replicative age of a cell in the specific compartment is j, increasing by one in each cell division. (b) Full model for ageing in progenitor compartment. The number of cells in each age class is n_j, and all cells age according to the modes of cell division (a). The cell influx into the compartment has a certain distribution of replicative age ι_j. The cell outflux from the compartment includes all differentiating cells and is denoted by the distribution . (Online version in colour.)

Inline graphic — Sketch of the basic model. (a) Three different modes of cell division in the focal progenitor compartment. Blue cells are cells within the compartment, red cells differentiate and leave the compartment. The replicative age of a cell in the specific compartment is j, increasing by one in each cell division. (b) Full model for ageing in progenitor compartment. The number of cells in each age class is n_j, and all cells age according to the modes of cell division (a). The cell influx into the compartment has a certain distribution of replicative age ι_j. The cell outflux from the compartment includes all differentiating cells and is denoted by the distribution . (Online version in colour.)