Table 3.
Proteins differentially expressed (P < 0.05) in infarcted mMCP-4 KO mice compared to infarcted WT congeners.
| Uniprot access code | Protein name | Log2 ratio |
|---|---|---|
| MYL1_MOUSE | Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) | 7.56 |
| B7ZCF1_MOUSE | 26S protease regulatory subunit 6A | 1.65 |
| A2AIM4_MOUSE | Tropomyosin beta chain | 1.39 |
| G5E850_MOUSE | Cytochrome b-5, isoform CRA_a | 1.32 |
| APOA1_MOUSE | Apolipoprotein A-I (Apo-AI) | 0.76 |
| E9Q5L2_MOUSE | Inter alpha-trypsin inhibitor, heavy chain 4 | 0.69 |
| ITIH3_MOUSE | Inter-alpha-trypsin inhibitor heavy chain H3 | 0.67 |
| LMNA_MOUSE | Prelamin-A/C [cleaved into: lamin-A/C] | 0.63 |
| DHE3_MOUSE | Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3) | 0.60 |
| CES1D_MOUSE | Carboxylesterase 1D (carboxylesterase 3) | 0.48 |
| RL35_MOUSE | 60S ribosomal protein L35 | 0.32 |
| RL8_MOUSE | 60S ribosomal protein L8 | 0.26 |
| Q8C2Q8_MOUSE | ATP synthase subunit gamma | 0.20 |
| NDUB9_MOUSE | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (complex I-B22) | –0.25 |
| RSSA_MOUSE | 40S ribosomal protein SA (37 kDa laminin receptor precursor) | –0.26 |
| NDUA1_MOUSE | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (complex I-MWFE) | –0.27 |
| KCRS_MOUSE | Creatine kinase S-type, mitochondrial (EC 2.7.3.2) | –0.28 |
| TELT_MOUSE | Telethonin (titin cap protein) | –0.34 |
| AT1B1_MOUSE | Sodium/potassium-transporting ATPase subunit beta-1 | –0.36 |
| RB11B_MOUSE | Ras-related protein Rab-11B | –0.36 |
| NDUB6_MOUSE | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (complex I-B17) | –0.37 |
| PCCA_MOUSE | Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCase subunit alpha) | –0.56 |
| TBA4A_MOUSE | Tubulin alpha-4A chain (Alpha-tubulin 4) | –0.57 |
| TIM50_MOUSE | Mitochondrial import inner membrane translocase subunit TIM50 | –0.70 |
| MOES_MOUSE | Moesin (membrane-organizing extension spike protein) | –0.90 |
| PGK1_MOUSE | Phosphoglycerate kinase 1 (EC 2.7.2.3) | –0.93 |
| RT4I1_MOUSE | Reticulon-4-interacting protein 1, mitochondrial | –1.09 |
| GSTA4_MOUSE | Glutathione S-transferase A4 (EC 2.5.1.18) (GST A4-4) | –1.19 |
| PLP2_MOUSE | Proteolipid protein 2 | –1.56 |
| G5E8T9_MOUSE | Hydroxyacyl glutathione hydrolase (mitochondrial) | –1.66 |
| COQ3_MOUSE | Ubiquinone biosynthesis O-methyltransferase, mitochondrial (EC 2.1.1.114) | –1.69 |
| DNPEP_MOUSE | Aspartyl aminopeptidase (EC 3.4.11.21) | –2.19 |
| ATAD1_MOUSE | ATPase family AAA domain-containing protein 1 (EC 3.6.1.3) (thorase) | –2.30 |
| PGAM1_MOUSE | Phosphoglycerate mutase 1 | –2.73 |
| EST1C_MOUSE | Carboxylesterase 1C (EC 3.1.1.1) | –2.78 |
| E9Q7L0_MOUSE | Protein Ogdhl (oxyglutarate dehydrogenase-like protein) | –4.06 |
| RMD1_MOUSE | Regulator of microtubule dynamics protein 1 (RMD-1) | –7.84 |
A positive number signifies an increase in mMCP-4 KO mice, while a negative number means a decrease. A chymase substrate, Apolipoprotein A1, is highlighted in bold.