. 2018 Aug 31;9:1002. doi: 10.3389/fphar.2018.01002

Table 3.

Antinociceptive activity and gastrointestinal transit inhibition by POMO in mice after s.c. administration.

	Antinociceptive activity^a	Gastrointestinal transit^b

	AD₅₀ (μg/kg, s.c.) (95% CI)	ED₅₀ (μg/kg, s.c.) (95% CI)
14-OMO	53 (48–58)^c	37 (35–39)
POMO	0.70 (0.63–0.77)	1.70 (0.80–3.58)
Morphine	6690 (4468–9348)^c	3800 (3400–4330)

^aDetermined in the hot-plate assay. Antinociceptive dose 50% with 95% confidence intervals (AD₅₀, 95% CI), (n = 6–8 mice per group). ^bDetermined in the charcoal test. Effective dose 50% with 95% confidence intervals (ED₅₀, 95% CI), (n = 8 mice per group). ^cData from Lattanzi et al. (2005).