Table 3.
Dose-response of the four selected small molecules (SMs) on Salmonella enterica subsp. enterica serotype Typhimurium in cell lines.
| SMs | Caco-2 cells | HD11 cells | THP-1 cells | |||
|---|---|---|---|---|---|---|
| MBC (μM) | IC50% (μM) | MBC (μM) | IC50% (μM) | MBC (μM) | IC50% (μM) | |
| SM1 | 25 | 12.5 < X < 25 | 6.25 | X < 3.215 | 100 | X < 50 |
| SM3 | 50 | 12.5 < X < 25 | 50 | X < 25 | 50 | 25 < X < 50 |
| SM4 | 25 | 12.5 < X < 25 | 25 | 12.5 < X < 25 | 25 | 12.5 < X < 25 |
| SM5 | 12.5 | 6.25 < X < 12.5 | 25 | X < 12.5 | 50 | X < 25 |
MBC: minimal bactericidal concentration; IC50%: 50% inhibitory concentration; X: estimated IC50%.