Fig. 4. Histologic responses between reflux-related subtype (true NERD+hypersensitivity group) and proton pump inhibitor-responsive functional heartburn groups. The degrees of basal cell hyperplasia (p=0.034), papillary elongation (p=0.023), and infiltration of intraepithelial T lymphocytes (p=0.034) were reduced significantly in the reflux-related group. ^*p<0.05. T lymphocytes, infiltration of intraepithelial T lymphocytes. NERD, nonerosive reflux disease; HE, hypersensitive esophagus.