Outcome of induction therapy defined as complete remission (CR), partial remission (PR), or treatment failure (TF) according to whether the spot protein/creatinine ratio (PCR) of the patient during induction therapy were reliable, problematic, or unreliable. As shown, those with unreliable spot PCRs were significantly less likely to have achieved CR and significantly more likely to have TF compared with those whose spot PCRs were reliable (P = 0.032), or compared with the combined cohort of reliable + generally reliable (P = 0.024).